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Gresham House Strategic plc operates as an investment fund, specializing in various capital injections including private investments in public equity (PIPEs), pre-initial public offering (pre-IPO) financing, growth and acquisition funding, and recovery capital. The fund directs its investments towards companies primarily within the financial services, media, information and communication technology, digital information and technology, healthcare, and life sciences industries. While its main geographic focus is on the United Kingdom and Europe, it also undertakes co-investments beyond Europe in collaboration with local venture capital firms.