The Direxion Daily Pharmaceutical & Medical Bull 3X ETF (PILL) is engineered to deliver daily investment outcomes equivalent to three times (300%) the performance of the S&P Pharmaceuticals Select Industry Index. This target is set before the deduction of any fees and expenses. However, it is not guaranteed that the fund will consistently attain its stated daily investment goal.

Corcept Therapeutics Incorporated

Organon & Co.

Liquidia Corporation

Axsome Therapeutics, Inc.

Enliven Therapeutics, Inc.

Definium Therapeutics, Inc.

Amneal Pharmaceuticals, Inc.

Jazz Pharmaceuticals plc

MBX Biosciences, Inc. Common Stock

Harmony Biosciences Holdings, Inc.

Healthcare

Direxion Daily Pharmaceutical & Medical Bull 3X ETF

PILL Holdings & Sector Breakdown

PILL Holdings & Sector Breakdown