Alfresa Holdings Corp. engages in the management of its subsidiaries that deal with wholesaling, manufacturing, import, and export of pharmaceutical products, diagnostic reagents, and medical devices. It operates through the following segments: Ethical Pharmaceuticals Wholesaling, Self-Medication Products Wholesaling, Manufacturing, and Medical-related. The Ethical Pharmaceuticals Wholesaling segment provides wholesale prescription drugs, medical diagnostic reagents, medical devices, equipment, and materials to hospitals, clinics, dispensing pharmacies, and other institutions.